A hematology analyzer (or hematology automaton) is a machine used to achieve a complete blood count (CBC) or hemogram. It completes a quantitative and qualitative analysis of the formed fundamentals of the blood: red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes).
What is the type of measurement technology used in hematology analyzers?
It is significant to know the counting technology used by the machine because it may cause consequences to vary. For hematology analyzers supplied by Hematology Analyzer Suppliers, we frequently distinguish between:
$ Flow cytometry :- This is the most state-of-the-art and expensive technique available today. It comprises moving the cells in a narrow stream before a laser beam. The laser beam hits them one by one and a light sensor captures the light reproduced from the cells. This is named laser flow cytometry. There is also fluorescence flow cytometry, which works on the same code as laser flow cytometry except that the kind of detection varies.
In general, flow cytometry consents for much more than just counting, such as examining the shape of cells and their internal and external structure. As a consequence, this method is rarely used for the sole purpose of counting cells.
$ Electrical impedance :- This method is used to regulate the number and volume of erythrocytes and thrombocytes. For this purpose, EDTA blood is thinned with an isotonic mixture inside the machine and aspirated through a capillary opening. The cells then move one by one through an electric voltage field where they encourage a pulse (surge in electrical resistance) according to their size. This makes it possible to discriminate between big cells and small ones and thus count them.
$ Laser scattering :- This method measures the size dispersals of particles. To do this, it calculates the angular variation in the strength of scattered light when a laser beam passes through an example of scattered particles. Large particles strew light at small angles about the laser beam, while minor particles throw light at larger angles. This means we can analyze the size of the particles from the deflection pattern they generate.
How to assess the presence of a hematology analyzer?
In addition to the measurement technology, it is significant to deliberate several other points:
- The number of parameters that the machine can deliver. This denotes all of the kinds of data the machine can provide concerning the measured elements. For instance, the number, capacity, and concentration of each element. Contingent on the apparatus, hematology analyzers supplied by Hematology Analyzer Suppliers can range from providing nine to over 50 parameters.
- White blood cell differentiation. Leukocytes can be alienated into three kinds: lymphocytes, monocytes, and granulocytes. Granulocytes can also be separated into three clusters: basophilic granulocytes, eosinophilic granulocytes, and neutrophilic granulocytes. There is therefore a total diversity of five kinds. Some analyzers do not bid leukocyte diversity.
What kinds of reagents are used in hematology?
When selecting reagents, it is very significant to pay close attention to the brands, contingent on whether the analyzer is in a closed system or not. Closed systems only admit reagents of the same brand as the machine. Analyzers companionable with any reagent brand are named “open.”
There are many kinds of reagents contingent on the precise applications (diagnostic and clinical) of the machine. To safeguard the proper working of the analyzer bought from a Hematology Analyzer Dealer, you will require to have calibrators, control solutions, diluents, and dyes.
